If you try to connect to an EXIM server with a certified certificate in order to send an email, you might get an error like this one:
Sending of the message failed
The message could not bt sent because the connection to the outgoing server mandrake.universe-corrupted.com timed out.
A quick work around is to change the server connection type from 465 SSL/TLS to 587 STARTTLS
It sounds crazy, but it fixes the issue.